John Gill Commentary Job 22:26

"For then shalt thou delight thyself in the Almighty, And shalt lift up thy face unto God." — Job 22:26 (ASV)

For then shall you have your delight in the Almighty
In the perfections of his nature, in the works of his hands, in his word and worship, in communion with him, and in the relation he stands in to his people as their covenant God and Father;

this would be the case when Job should be more and better acquainted with God, and with the law or doctrine his month, and the words of his lips, and should return unto him with his whole heart; and when his affections should be taken off all earthly riches; when he should look upon gold as dust, and the gold of Ophir as the stones of the brook, and God should be to him his gold and his silver; then, and not until then, could he have true delight and complacency in God:

and shall lift up your face unto God ;
in prayer, as Sephorno interprets it, with an holy confidence, boldness, and cheerfulness; as a believer in Christ may, having on his righteousness, and having his heart sprinkled from an evil conscience by his blood; such an one can appear before God, and lift up his face to him, as without spot, so without confusion, shame, and blushing, without a load of guilt upon him, without fear of wrath or punishment, and of being repulsed; see (Job 11:15) .