John Gill Commentary John 11:48

"If we let him thus alone, all men will believe on him: and the Romans will come and take away both our place and our nation." — John 11:48 (ASV)

If we let him thus alone
Going about from place to place, teaching the people, and doing such miracles:

all men will believe on him ;
the whole nation will receive him as the Messiah, and proclaim him their king, and yield a cheerful obedience to all his commands:

the Romans will come ;
against us, with their powerful armies; interpreting the setting him up as Messiah, to be an instance of rebellion against Caesar, and his government:

and take away both our place and nation ;
that is, will destroy the temple, their holy place, the place of their religion and worship; and their city, the place of their habitation, and lay waste their country; and take away from them that little share of power and government they had, and strip them both of their civil and religious privileges: the Persic version renders it, "they will take away our place, and make a decree against our religion".