John Gill Commentary Lamentations 2:22

"Thou hast called, as in the day of a solemn assembly, my terrors on every side; And there was none that escaped or remained in the day of Jehovah`s anger: Those that I have dandled and brought up hath mine enemy consumed." — Lamentations 2:22 (ASV)

You have called, as in a solemn day, my terrors round about, &c.] Terrible enemies, as the Chaldeans; these came at the call of God, as soldiers at the command of their general; and in as great numbers as men from all parts of Judea flocked to Jerusalem on any of the three solemn feasts of passover, pentecost, and tabernacles.

The Targum paraphrases it very foreign to the sense; "you shall proclaim liberty to your people, the house of Israel, by the Messiah, as you did by Moses and Aaron on the day of the passover:" so that in the day of the Lord's anger none escaped or remained; in the city of Jerusalem, and in the land of Judea; either they were put to death, or were carried captive; so that there was scarce an inhabitant to be found, especially after Gedaliah was slain, and the Jews left in the land were carried into Egypt.

Those that I have swaddled and brought up has my enemy consumed; or "whom I could span," as Broughton; or "handled"; whose limbs she had stroked with her hands, whom she had swathed with bands, and had carried in her arms, and had most carefully and tenderly brought up: by those she had "swaddled" are meant the little ones; and by those she had "brought up" the greater ones, as Aben Ezra observes; but both the enemy, the Chaldeans, consumed and destroyed without mercy, without regard to their tender years, or the manner in which they were brought up; but as if they were nourished like lambs for the day of slaughter.