John Gill Commentary Luke 22:42

"saying, Father, if thou be willing, remove this cup from me: nevertheless not my will, but thine, be done." — Luke 22:42 (ASV)

Saying, Father, if you are willing
If it be consistent with your will of saving sinners, and which you have declared to me, and I have undertaken to perform: the other evangelists say, "if it be possible"; (See Gill on Matthew 26:39) remove this cup from me ;
meaning, either his present sorrows and distress, or his approaching sufferings and death, which he had in view, or both: nevertheless not my will ;
as man, for Christ had an human will distinct from, though not contrary to his divine will: but your be done ;
which Christ undertook, and came into this world to do; and it was his meat and drink to do it, and was the same with his own will, as the Son of God; (See Gill on Matthew 26:39), and (See Gill on Matthew 26:42).