John Gill Commentary Luke 8:43

"And a woman having an issue of blood twelve years, who had spent all her living upon physicians, and could not be healed of any," — Luke 8:43 (ASV)

And a woman having an issue of blood twelve years
The Persic version reads, "there was a woman in that city" in the city of Capernaum; (See Gill on Matthew 9:20).

Which had spent all her living upon physicians ;
she had applied to one physician and another, and had consumed all her substance in this way:

neither could be healed of any ;
though she had followed the directions and prescriptions of many, who pretended they were able to cure her; (See Gill on Mark 5:26).