John Gill Commentary Mark 14:21

"For the Son of man goeth, even as it is written of him: but woe unto that man through whom the Son of man is betrayed! good were it for that man if he had not been born." — Mark 14:21 (ASV)

The son of man indeed goes Out of this world by death,

as it is written ; both in the book of God's decrees, and in the Scriptures of the Old Testament;

but woe to that man by whom the son of man is betrayed ! whose sin will not be excused, nor lessened by fulfilling the decrees of God, and by accomplishing the prophecies of the Bible:

good were it for that man if he had never been born ; so aggravating will be his crime, so dreadful his punishment; (See Gill on Matthew 26:24).