John Gill Commentary Proverbs 3:7

"Be not wise in thine own eyes; Fear Jehovah, and depart from evil:" — Proverbs 3:7 (ASV)

Be not wise in your own eyes
So as to act independently of God; not to trust in him, nor acknowledge him, nor seek to him for help and direction; nor ask nor take the advice of others; but, being conceited and self-sufficient, lean to your own understanding, as being wise enough to conduct all affairs in life by your own discretion; and in matters of religion wiser than your teachers, and even than the Scriptures, being wise above that which is written; pleasing yourself with your own wisdom, as exceeding others; glorying in it as your own acquisition, and not ascribing it to God, so far as it any ways deserves the name of wisdom; though for the most part that which men glory in, and are conceited of, is not wisdom, but folly; and at least it is their folly to boast of it and be elated with it; see (Isaiah 5:21) (Romans 12:16) ;

fear the Lord ;
which is true wisdom; and, where this is not, there is none, let men be ever so conceited; and where this is there is humility; these two go together, and make a man wise, rich, and honourable, (Proverbs 22:4) . The fear of the Lord is opposed to pride, high-mindedness, and vain conceit, (Romans 11:20) ; this includes reverence of God, faith in him, dependence on him, acknowledgment of him, seeking to him for direction, and carefulness not to offend him;

and depart from evil ;
from the evil of self-confidence and self-conceit, and from all other evil; the fear of God influences men to avoid sin, and abstain from all appearance of it; by means and through the exercise of it men forsake it, and keep at a distance from it, (Proverbs 16:6) . Nehemiah could not do as others did, because of the fear of the Lord; and Job was a man that feared God, and therefore he avoided that which was evil, (Nehemiah 5:15) (Job 1:1) .