John Gill Commentary Psalms 109:22

"For I am poor and needy, And my heart is wounded within me." — Psalms 109:22 (ASV)

For I am poor and needy
As he was in human nature, being born of poor parents, brought up in a mean manner, had not where to lay his head, and was ministered to by others; though he was Lord of all, and immensely rich in the perfections of his nature, and in his vast empire and dominion, and the revenues arising from thence; see (2 Corinthians 8:9) . It may here chiefly respect his helpless and forlorn estate as man, at the time of his sufferings and death; see (Psalms 40:17) .

And my heart is wounded within me ;
with the sins of his people on him, with a sense of divine wrath, and when under divine desertions, especially when his soul was exceeding sorrowful, even unto death, (Matthew 26:38) (Psalms 40:12) .