John Gill Commentary Psalms 119:157

"Many are my persecutors and mine adversaries; [Yet] have I not swerved from thy testimonies." — Psalms 119:157 (ASV)

Many [are] my persecutors and mine enemies
Because they were his enemies, therefore they were his persecutors; and they became enemies to him, or hated him, because of his religion, and on that account persecuted him:

and this has always been the lot and case of God's people in all ages; and whose persecutors are many, even the whole world, as well as fierce and furious;

[yet] do I not decline from your testimonies ;
from reading and hearing the word of God; and from embracing and professing the doctrines contained in it; and from the worship of God according to it, for which he was hated and persecuted:

yet none of these things moved him from them, which showed that his heart was principled with the grace of God; for otherwise, when persecution arises because of the word, carnal professors are offended, and apostatize from it; see (Matthew 13:22) (Acts 24:23Acts 24:24) .