John Gill Commentary Psalms 80:11

"It sent out its branches unto the sea, And its shoots unto the River." — Psalms 80:11 (ASV)

She sent out her boughs to the sea
The Mediterranean, or midland sea, which was the border of the land of Canaan to the west:

and her branches to the river
the river Euphrates, which was its border to the east; see (Deuteronomy 11:24) . This, in the spiritual sense of it, will have its accomplishment in the church of Christ, when he shall have dominion from sea to sea, and from the river to the ends of the earth, (Psalms 72:8) . The Targum is, ``she sent out her disciples to the great sea, and to the river Euphrates her babes;'' or sucklings.