Matthew Henry Commentary 1 Timothy 4:1-5

"But the Spirit saith expressly, that in later times some shall fall away from the faith, giving heed to seducing spirits and doctrines of demons, through the hypocrisy of men that speak lies, branded in their own conscience as with a hot iron; forbidding to marry, [and commanding] to abstain from meats, which God created to be received with thanksgiving by them that believe and know the truth. For every creature of God is good, and nothing is to be rejected, if it be received with thanksgiving: for it is sanctified through the word of God and prayer." — 1 Timothy 4:1-5 (ASV)

The Holy Spirit, both in the Old and the New Testament, spoke of a general turning from the faith of Christ, and the pure worship of God. This was to come during the Christian dispensation, for those are called the latter days.

False teachers forbid as evil what God has allowed, and command as a duty what He has left indifferent.

We find the exercise of watchfulness and self-denial in attending to the requirements of God's law, without being tasked with imaginary duties that reject what He has allowed. But nothing justifies an intemperate or improper use of things; and nothing will be good to us unless we seek the Lord's blessing upon it through prayer.