An overwhelming consensus among commentators identifies the “little horn” in this verse as Antiochus IV Epiphanes, a Greek king from the Seleucid empire. He rose from a position of relative obscurity to become a powerful and cruel persecutor of the Jewish people in the 2nd century BC. His campaigns south (Egypt), east (Persia), and into Judea (“the glorious land”) are seen as a direct fulfillment of this prophecy.