Commentators like Matthew Henry and John Gill highlight a powerful spiritual metaphor in this verse. Since the head symbolizes judgment, knowledge, and faith, leprosy appearing on the head or beard represents the danger of corrupted thinking, false doctrines, and wicked principles. This serves as a warning that when sin seizes the mind, it leads to a state of 'utter uncleanness.' Soundness in faith is presented as the defense against this spiritual leprosy.