Multiple commentators highlight that the 'instruction' which is 'life' points directly to Jesus Christ. They draw parallels between this verse and New Testament passages like John 1:4 ('In him was life') and 1 John 5:12 ('He that hath the Son hath life'). The wisdom to be held onto is not merely a set of rules, but an interest in Christ's salvation, who is the ultimate source of spiritual life.